KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
16.67
Human Site:
S381
Identified Species:
33.33
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
S381
N
P
L
P
E
T
D
S
Q
P
I
P
P
S
G
Chimpanzee
Pan troglodytes
XP_511742
777
85768
S381
N
P
L
P
E
T
D
S
Q
P
I
P
P
S
G
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
S381
N
P
L
P
E
T
D
S
Q
P
I
P
P
S
G
Dog
Lupus familis
XP_540486
782
86005
P385
T
P
L
P
E
T
D
P
Q
P
I
A
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
S381
A
P
L
P
E
T
D
S
Q
P
I
T
P
C
S
Rat
Rattus norvegicus
Q9JJ50
776
86228
S381
A
P
L
P
E
T
D
S
Q
P
I
T
S
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
N381
Q
N
G
E
S
E
E
N
H
E
Q
F
L
K
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
A379
E
V
Q
I
D
E
F
A
A
N
M
R
T
Q
V
Honey Bee
Apis mellifera
XP_393989
830
92147
E380
G
E
V
D
N
Q
M
E
E
F
V
N
A
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
S378
V
N
R
M
K
S
D
S
S
R
G
R
S
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
I283
N
S
A
S
S
E
P
I
V
P
V
V
E
S
K
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
N378
P
V
E
A
E
N
I
N
L
F
A
T
L
V
D
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
100
100
80
N.A.
73.3
66.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
100
80
N.A.
73.3
66.6
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
9
0
0
0
9
9
0
9
9
9
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% C
% Asp:
0
0
0
9
9
0
59
0
0
0
0
0
0
0
9
% D
% Glu:
9
9
9
9
59
25
9
9
9
9
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
17
0
9
0
0
0
% F
% Gly:
9
0
9
0
0
0
0
0
0
0
9
0
0
0
34
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
9
0
0
50
0
0
9
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
9
% K
% Leu:
0
0
50
0
0
0
0
0
9
0
0
0
17
9
0
% L
% Met:
0
0
0
9
0
0
9
0
0
0
9
0
0
0
0
% M
% Asn:
34
17
0
0
9
9
0
17
0
9
0
9
0
0
0
% N
% Pro:
9
50
0
50
0
0
9
9
0
59
0
25
42
0
0
% P
% Gln:
9
0
9
0
0
9
0
0
50
0
9
0
0
9
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
9
0
17
0
0
9
% R
% Ser:
0
9
0
9
17
9
0
50
9
0
0
0
17
42
17
% S
% Thr:
9
0
0
0
0
50
0
0
0
0
0
25
9
0
0
% T
% Val:
9
17
9
0
0
0
0
0
9
0
17
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _